Functional gastrointestinal disorders, lifestyle habits, and smartphone addiction in adolescents

  • Mauro Cinquetti | Maternal and Child Department, Azienda ULSS 9 Scaligera, Verona, Italy.
  • Marco Biasin Department of Surgical Sciences, Dentistry, Gynecology and Pediatrics, University of Verona, Verona, Italy.
  • Marco Ventimiglia IBD Unit, Villa-Sofia Hospital, Palermo, Italy.
  • Linda Balanzoni Maternal and Child Department - Azienda ULSS 9 Scaligera, Italy.
  • Denise Signorelli Health Management, Azienda ULSS 9 Scaligera, Verona, Italy.
  • Angelo Pietrobelli Department of Surgical Sciences, Dentistry, Gynecology and Pediatrics, University of Verona, Verona, Italy, and Pennington Biomedical Research Center, Baton Rouge, LA, United States.


We performed a cross-sectional study. In spring 2019, 1,594 students (mean age 12.87 years) completed a questionnaire on gastrointestinal symptoms, smartphone use, Quality of Life (QoL), dietary habits, and physical activity. Based on the Rome IV criteria, 30.9% of participants met the symptom-based criteria for FGIDs and 8.9% experienced ≥2 disorders simultaneously. Well-being was less frequently reported by children with FGIDs than others (29.0% vs. 48.2%; p < 0.001). Participants addicted to smartphones reported low than others well-being (18.0% vs. 25.8%; p < 0.001), they also showed higher prevalence of FGIDs [Odds Ratio (OR), 1.98; 95% Confidence Interval (CI), 1.47–2.68; p < 0.001]. Among dietary habits, skipping breakfast (OR, 1.50; 95% CI, 1.09–2.05; p = 0.01) and low fruit consumption (OR, 1.66; 95% CI, 1.172.36; p = 0.005) were more frequent in participants with FGIDs. FGIDs are common in pediatric populations. FGIDs have an impact on QoL. Some dietary habits and physical activity are associated with these disorders. Smartphone addiction was found to be associated with FGIDs.



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Boronat AC, Ferreira-Maia AP, Matijasevich A, Wang Y-P. Epidemiology of functional gastrointestinal disorders in children and adolescents: A systematic review. World J Gastroenterol 2017;23:3915-27. DOI:

Talley NJ. Functional gastrointestinal disorders as a public health problem. Neurogastroenterol Motil 2008;20:121-9. DOI:

Drossman DA, Hasler WL. Rome IV-Functional GI Disorders: Disorders of gut-brain interaction. Gastroenterology 2016;150:1257-61. DOI:

Drossman DA. Functional gastrointestinal disorders: history, pathophysiology, clinical features, and Rome IV. Gastroenterology 2016;150:1262-79.E2. DOI:

Robin SG, Keller C, Zwiener R, et al. Prevalence of pediatric functional gastrointestinal disorders utilizing the Rome IV Criteria. J Pediatr 2018;195:134-9. DOI:

Saps M, Velasco-Benitez CA, Langshaw AH, Ramírez-Hernández CR. Prevalence of functional gastrointestinal disorders in children and adolescents: comparison between Rome III and Rome IV criteria. J Pediatr 2018;199:212-6. DOI:

Xu J-R, Shang L, Si W-L, et al. A population-based study of associations between functional gastrointestinal disorders and psychosocial characteristics in Xi’an, China. Neurogastroenterol Motil 2013;25:617-e467. DOI:

Shau J-P, Chen P-H, Chan C-F, et al. Fast foods--are they a risk factor for functional gastrointestinal disorders? Asia Pac J Clin Nutr 2016;25:393-401.

Moding M, Ohlsson B. The role of fermentable carbohydrates and beverages in the symptomatology of functional gastrointestinal disease. Scand J Gastroenterol 2017;52:1224-34. DOI:

Pasquale CD, Sciacca F, Hichy Z. Italian validation of smartphone addiction scale short version for adolescents and young adults (SAS-SV). Psychology 2017;08:1513. DOI:

Rockett HRH, Breitenbach M, Frazier AL, et al. Validation of a youth/adolescent food frequency questionnaire. Prev Med 1997;26:808-16. DOI:

Topolski TD, LoGerfo J, Patrick DL, et al. The rapid assessment of physical activity (RAPA) among older adults. Prev Chronic Dis 2006;3:A118.

Brazier JE, Harper R, Jones NM, et al. Validating the SF-36 health survey questionnaire: new outcome measure for primary care. BMJ 1992;305:160-4. DOI:

Scarpato E, Kolacek S, Jojkic-Pavkov D, et al. Prevalence of functional gastrointestinal disorders in children and adolescents in the Mediterranean Region of Europe. Clin Gastroenterol Hepatol 2018;16:870-6. DOI:

Varni JW, Bendo CB, Nurko S, et al. Health-related quality of life in pediatric patients with functional and organic gastrointestinal diseases. J Pediatr 2015;166:85-90. DOI:

Peralta-Palmezano JJ, Guerrero-Lozano R. Prevalence of functional gastrointestinal disorders in school children and adolescents. Korean J Gastroenterol 2019;73:207-12. DOI:

Adeyemo MA, Spiegel BMR, Chang L. Meta-analysis: do irritable bowel syndrome symptoms vary between men and women? Aliment Pharmacol Ther 2010;32:738-55. DOI:

Varni JW, Shulman RJ, Self MM, et al. Gastrointestinal symptoms predictors of health-related quality of life in pediatric patients with functional gastrointestinal disorders. Qual Life Res 2017;26:1015-25. DOI:

Strid H, Simrén M, Störsrud S, et al. Effect of heavy exercise on gastrointestinal transit in endurance athletes. Scand J Gastroenterol 2011;46:673-7. DOI:

Ohlsson B, Manjer J. Physical inactivity during leisure time and irregular meals are associated with functional gastrointestinal complaints in middle-aged and elder subjects. Scand J Gastroenterol 2016;51:1299-307. DOI:

Varney J, Barrett J, Scarlata K, et al. FODMAPs: food composition, defining cutoff values and international application. J Gastroenterol Hepatol 2017;32:53-61. DOI:

Vakhshuury M, Khoshdel A. The relation between dietary patterns and functional gastrointestinal disorders among Iranian military men. Adv Biomed Res 2019;8:2. DOI:

Kwon M, Lee J-Y, Won W-Y, et al. development and validation of a smartphone addiction scale (SAS). PLoS One 2013;8:e56936. DOI:

Sohn S, Rees P, Wildridge B, et al. Prevalence of problematic smartphone usage and associated mental health outcomes amongst children and young people: a systematic review, meta-analysis and GRADE of the evidence. BMC Psychiatry 2019;19:356. DOI:

Choi S-W, Kim D-J, Choi J-S, et al. Comparison of risk and protective factors associated with smartphone addiction and Internet addiction. J Behav Addict 2015;4:308-14. DOI:

Kim Y-J, Jang HM, Lee Y, et al. Effects of internet and smartphone addictions on depression and anxiety based on propensity score matching analysis. Int J Environ Res Public Health 2018;15. DOI:

Elhai JD, Dvorak RD, Levine JC, Hall BJ. Problematic smartphone use: A conceptual overview and systematic review of relations with anxiety and depression psychopathology. J Affect Disord 2017;207:251-9. DOI:

Vahedi Z, Saiphoo A. The association between smartphone use, stress, and anxiety: A meta-analytic review. Stress Health 2018;34:347-58. DOI:

Koloski NA, Jones M, Kalantar J, et al. The brain--gut pathway in functional gastrointestinal disorders is bidirectional: a 12-year prospective population-based study. Gut 2012;61:1284-90. DOI:

Wouters MM, Boeckxstaens GE. Is there a causal link between psychological disorders and functional gastrointestinal disorders? Expert Rev Gastroenterol Hepatol 2016;10:5-8. DOI:

Bulut Çakmak B, Özkula G, Işıklı S, et al. Anxiety, depression, and anger in functional gastrointestinal disorders: A Cross-sectional observational study. Psychiatry Res 2018;268:368-72. DOI:

Functional gastrointestinal disorders, dietary habits, quality of life, Rome IV, smartphone
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How to Cite
Cinquetti, M., Biasin, M., Ventimiglia, M., Balanzoni, L., Signorelli, D., & Pietrobelli, A. (2021). Functional gastrointestinal disorders, lifestyle habits, and smartphone addiction in adolescents. La Pediatria Medica E Chirurgica, 43(1).