Lichen sclerosus in pediatric age: A new disease or unknown pathology? Experience of single centre and state of art in literature


Submitted: 8 September 2021
Accepted: 27 January 2022
Published: 1 March 2022
Abstract Views: 1375
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Authors

  • Rossella Angotti Pediatric Surgery, Department of Women and Children, S. Maria alle Scotte Hospital, University of Siena, Siena, Italy.
  • Giulia Fusi Pediatric Surgery, Department of Medical, Surgical and Neurological Sciences, S. Maria alle Scotte Hospital, University of Siena, Siena, Italy.
  • Elena Coradello Department of Medical, Surgical and Neurological Sciences, University of Siena, Italy.
  • Clelia Miracco Pathological Anatomy Unit, Department of Medical, Surgical and Neurological Science, S. Maria alle Scotte Hospital, University of Siena, Siena, Italy.
  • Francesco Ferrara Pediatric Surgery, Department of Women and Children, S. Maria alle Scotte Hospital, University of Siena, Siena, Italy.
  • Marina Sica Pediatric Surgery, Department of Women and Children, S. Maria alle Scotte Hospital, University of Siena, Siena, Italy.
  • Alessandra Taddei Pediatric Surgery, Department of Women and Children, S. Maria alle Scotte Hospital, University of Siena, Siena, Italy.
  • Gabriele Vasta Pediatric Surgery, Department of Medical, Surgical and Neurological Sciences, S. Maria alle Scotte Hospital, University of Siena, Siena, Italy.
  • Mario Messina Pediatric Surgery, Department of Women and Children; Pediatric Surgery, Department of Medical, Surgical and Neurological Sciences, S. Maria alle Scotte Hospital, University of Siena, Siena, Italy.
  • Francesco Molinaro Pediatric Surgery, Department of Women and Children; Pediatric Surgery, Department of Medical, Surgical and Neurological Sciences, S. Maria alle Scotte Hospital, University of Siena, Siena, Italy.

Lichen Sclerosus (LS) is a chronic inflammatory skin disease with unknown etiology. In pediatric age the main disease “lichenlinked” is the phimosis in male. This is a retrospective study that reports the experience of our clinic and review of the literature. We included all patients affected by pathological phimosis, treated by circumcision between January 2015 and May 2020, older than 6 years old and with an histopathological diagnosis of lichen sclerosus. The aim was to identify prognostic factors based on histological report to plan the clinical management of patients. Statistical analysis was done. We included 207 patients. The mean age of children was 9,78 years (5-18 years, DS±3.29). Based on the histological features we divided patients in 2 groups: early lesions (70/207, 34%) and advanced (137/207, 66%). In term of complications lichen linked we considered meatal stenosis that needed of urethral dilatations. We included 7 patients (7/207, 3,4%). We report P value Statistical Significance in many aspects. An early diagnosis of LS and surgical treatment of foreskin are essential to prevent early and late complications in children. The size of sample is a limit of the study but results encourage our management.


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Angotti, R., Fusi, G., Coradello, E., Miracco, C., Ferrara, F., Sica, M., Taddei, A., Vasta, G., Messina, M., & Molinaro, F. (2022). Lichen sclerosus in pediatric age: A new disease or unknown pathology? Experience of single centre and state of art in literature. La Pediatria Medica E Chirurgica, 44(1). https://doi.org/10.4081/pmc.2022.275

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