https://doi.org/10.4081/pmc.2023.308
Ureteropelvic junction obstruction in children by polar vessels: histological examination result
Submitted: 17 January 2023
Accepted: 15 May 2023
Published: 30 May 2023
Accepted: 15 May 2023
Abstract Views: 675
PDF: 335
HTML: 8
HTML: 8
Publisher's note
All claims expressed in this article are solely those of the authors and do not necessarily represent those of their affiliated organizations, or those of the publisher, the editors and the reviewers. Any product that may be evaluated in this article or claim that may be made by its manufacturer is not guaranteed or endorsed by the publisher.
All claims expressed in this article are solely those of the authors and do not necessarily represent those of their affiliated organizations, or those of the publisher, the editors and the reviewers. Any product that may be evaluated in this article or claim that may be made by its manufacturer is not guaranteed or endorsed by the publisher.
Authors
In children, ureteropelvic junction obstruction (UPJO) is mostly caused by intrinsic factors (IUPJO) such as abnormal amounts of muscle and collagen deposition; extrinsic UPJO are rare and often due to crossing vessels (CVs). What is not clear is whether there is also intrinsic UPJ pathology in patients with CV. The aim of our study was to compare the histology of the two types of obstruction and to determine whether these histologic features are distinguishable enough to enable to identify the cause of obstruction based on histologic appearance alone. We retrospectively reviewed pathology reports of 38 children with UPJO that underwent surgery in our hospital from 2008 to 2022. The intrinsic and extrinsic groups consisted of 18 and 20 patients, respectively. After ematoxylin-eosin and Gomori's trichrome staining the specimens were scored for fibrosis and muscular hypertrophy in histhopatology, and CD117 antibody were used to detect interstitial Cajal-like cells. In our study, histological analyses revealed no differences between the CV and IUPJO specimens in terms of presence and degree of fibrosis and muscular hypertrophy; likewise, for presence of interstitial Cajal-like cells.
Hsu TH, Streem SB, Nakada SY. Management of upper urinary tract obstruction. In: Wein A, Kavoussi L, Novick A, Partin A and Peters C, eds. Campbell -Walsh Urology. Philadelphia, PHL: Saunders; Vol. 2.
Mut T, Acar Ö, Oktar T, et al. Intraoperative inspection of the ureteropelvic junction during pyeloplasty is not sufficient to distinguish between extrinsic and intrinsic causes of obstruction: Correlation with histological analysis. J Pediatr Urol 2016;12,223.e1-223.e6.
DOI: https://doi.org/10.1016/j.jpurol.2016.02.016
Meng MV, Stoller ML. Hellström technique revisited: laparoscopic management of ureteropelvic junction obstruction. Urology 2003;62:404-409.
DOI: https://doi.org/10.1016/S0090-4295(03)00562-4
Godbole P, Mushtaq I, Wilcox D, Duffy P. Laparoscopic transposition of lower pole vessels the “vascular hitch”: an alternative to dismembered pyeloplasty for pelvic-ureteric junction obstruction in children. J Pediatr Urol 2006;2:285-289.
DOI: https://doi.org/10.1016/j.jpurol.2005.11.017
Chiarenza SF, Bleve C, Fasoli L, et al. Ureteropelvic junction obstruction in children by polar vessels. Is laparoscopic vascular hitching procedure a good solution? Single center experience on 35 consecutive patients. J Pediatr Surg 2016;51:310-4.
DOI: https://doi.org/10.1016/j.jpedsurg.2015.10.005
Hellström J, Giertz G, Lindblom K. Pathogenesis and treatment of hydronephrosis. In: Presentedat VIII Congreso de la Sociedad International de Urologia, Paris, France 1949.
Chapman TL. Urology in Outline. Edinburgh, London: Churchill. Livingstone, 1959; 82.
Wong MCY, Piaggio G, Damasio MB, et al. Hydronephrosis and crossing vessels in children: Optimization of diagnostic-therapeutic pathway and analysis of color Doppler ultrasound and magnetic resonance urography diagnostic accuracy. J Pediatr Urology 2018;14, 68.e1-68.e6.
DOI: https://doi.org/10.1016/j.jpurol.2017.09.019
Park JM, Bloom DA. The pathophysiology of UPJ obstruction. Curr Concepts Urol Clin North Am 1998;25:161-9.
DOI: https://doi.org/10.1016/S0094-0143(05)70004-5
Baker LA, Gomez RA. Embryonic development of the ureter and bladder: acquisition of smooth muscle. J Urol 1998;160:545-50.
DOI: https://doi.org/10.1016/S0022-5347(01)62956-2
Herts BR. Helical CT and CT angiography for the identification of crossing vessels at the ureteropelvic junction. Urol Clin North Am 1998;25:259-69.
DOI: https://doi.org/10.1016/S0094-0143(05)70013-6
Hashim H, Woodhouse CRJ. Ureteropelvic Junction Obstruction. European Urology Supplements 2012; 11:25-32.
DOI: https://doi.org/10.1016/j.eursup.2012.01.004
Gundeti MS, Reynolds WS, Duffy PG, Mushtaq I. Further experience with the vascular hitch (laparoscopic transposition of lower pole crossing vessels): an alternate treatment for pediatric ureterovascular ureteropelvic junction obstruction. J Urol 2008;180:1832-6.
DOI: https://doi.org/10.1016/j.juro.2008.05.055
Stern JM, Park S, Anderson LK, et al. Functional assessment of crossing vessels as etiology of ureteropelvic junction obstruction. Urology 2007;69:1022-4.
DOI: https://doi.org/10.1016/j.urology.2007.02.055
Weiss DA, Kadakia S, Kurzweil R, et al. Detection of crossing vessels in pediatric ureteropelvic junction obstruction: Clinical patterns and imaging findings. J Pediatr Urol 2015;11:173.e1-5.
DOI: https://doi.org/10.1016/j.jpurol.2015.04.017
Nerli RB, Jayanthi VR, Reddy M, Koura A. Pelvi-ureteric junction obstruction with crossing renal vessels: a case report of failed laparoscopic vascular hitch. J Pediatr Urol 2009;5:147-50.
DOI: https://doi.org/10.1016/j.jpurol.2008.09.009
Janetschek G, Peschel R, Altarac S, Bartsch G. Laparoscopic and retroperitoneoscopic repair of ureteropelvic junction obstruction. Urology 1996;47:311-6.
DOI: https://doi.org/10.1016/S0090-4295(99)80444-0
Ellerkamp V, Kurth RR, Schmid E, et al. Differences between intrinsic and extrinsic ureteropelvic junction obstruction related to crossing vessels: histology and functional analyses. World J Urol 2016;34:577-83.
DOI: https://doi.org/10.1007/s00345-015-1645-x
Issi O, Deliktas H, Gedik A, et al. Does the Histopathologic Pattern of the Ureteropelvic Junction Affect the Outcome of Pyeloplasty? Urol J 2015;12:2028-31.
Cancian M, Pareek G, Caldamone A, et al. Histopathology in ureteropelvic junction obstruction with and without crossing vessels. Urology 2017;107:209-13.
DOI: https://doi.org/10.1016/j.urology.2017.05.013
Santicioli P, Maggi CA. Myogenic and neurogenic factors in the control of pyeloureteral motility and ureteral peristalsis. Pharmacol Rev 1998;50:683-722.
Kodela P, Apoznanski W, Wozniak Z, Pupka A. Changes in interstitial cell of Cajal-like cells density in congenital ureteropelvic junction obstruction. Int Urol Nephrol 2012;44:7-12.
DOI: https://doi.org/10.1007/s11255-011-9970-5
Kuvel M, Canguven O, Murtazaoglu M, Albayrak S. Distribution of Cajal like cells and innervation in intrinsic ureteropelvic junction obstruction. Arch Ital Urol Androl 2011;83:128-32.
How to Cite
Piro, E., Colombini, F., Brugnoni, M., Perilli, D., Abati, L. C., Zocca, V., … D’Alessio, A. (2023). Ureteropelvic junction obstruction in children by polar vessels: histological examination result. La Pediatria Medica E Chirurgica, 45(1). https://doi.org/10.4081/pmc.2023.308
Copyright (c) 2023 the Author(s)
This work is licensed under a Creative Commons Attribution-NonCommercial 4.0 International License.
PAGEPress has chosen to apply the Creative Commons Attribution NonCommercial 4.0 International License (CC BY-NC 4.0) to all manuscripts to be published.
Similar Articles
- Sara Uccella, Agnese De Carli, Ida Sirgiovanni, Paola Schiavolin, Giuseppe Damiano, Beatrice Ghirardi, Francesca Maglioli Carpano, Laura Bassi, Silvana Gangi, Odoardo Picciolini, Monica Fumagalli, Fabio Mosca, Survival rate and neurodevelopmental outcome of extremely premature babies: an 8-year experience of an Italian single neonatal tertiary care center , La Pediatria Medica e Chirurgica: Vol. 37 No. 3 (2015)
- Majid Reza Akbarizadeh, Fereshteh Ghaljaei, Alireza Hasanzadeh, Abdolghani Abdollahimohammad, Mahin Naderifar, The effect of an educational program on illness uncertainty in mothers of children with type 1 diabetes: a quasi-experimental study , La Pediatria Medica e Chirurgica: Vol. 46 No. 1 (2024)
- Francesco Tandoi, Laura Morlacchi, Angela Bossi, Massimo Agosti, Introducing complementary foods in the first year of life , La Pediatria Medica e Chirurgica: Vol. 39 No. 4 (2017)
- C. Ripoli, A. Pinna, S. Marras, M.L. Fenu, A.M. Nurchi, A distal renal tubular acidosis showing hyperammonemia and hyperlactacidemia , La Pediatria Medica e Chirurgica: Vol. 34 No. 4 (2012)
- Salvatore Arena, Tiziana Russo, Patrizia Perrone, Carmelo Romeo, Operative cystoscopy in the neonatal period , La Pediatria Medica e Chirurgica: Vol. 38 No. 3 (2016)
- Silvia Richetta, Antonio Andreacchio, Sergio Monforte, Percutaneous Achilles tenotomy using a 18 gauge needle in the treatment of clubfoot with Ponseti method , La Pediatria Medica e Chirurgica: Vol. 44 No. s1 (2022)
- Francesco Marras, Chiara Asti, Corrado Ciatti, Stefano Pescia, Cristian Locci, Francesco Pisanu, Carlo Doria, Gianfilippo Caggiari, Congenital hip dysplasia: The importance of early screening and treatment , La Pediatria Medica e Chirurgica: Vol. 44 No. s1 (2022)
- Fabio Mosca, Maria Lorella Giannì, Human milk: composition and health benefits , La Pediatria Medica e Chirurgica: Vol. 39 No. 2 (2017)
- Luisella Pedrotti, Barbara Bertani, Gabriella Tuvo, Redento Mora, Luca Marin, Federica De Rosa, Achilles tendon surgery in clubfoot: Are long term sequelae predictable? , La Pediatria Medica e Chirurgica: Vol. 44 No. 1 (2022)
- Ismael José Dorta Luis, Paloma González Carretero, Carmen Luz Marrero Pérez, Ignacio Hernández Cabezudo, Antonio López Figueroa, Andrea González Palau, Pulling out a broken catheter using interventional radiology in a preterm. Neonatal intensive care , La Pediatria Medica e Chirurgica: Vol. 43 No. 1 (2021)
You may also start an advanced similarity search for this article.