Effect of prematurity on fat mass distribution and blood pressure at prepubertal age: a follow-up study


Submitted: 17 November 2014
Accepted: 17 November 2014
Published: 31 August 2013
Abstract Views: 801
PDF: 1193
Publisher's note
All claims expressed in this article are solely those of the authors and do not necessarily represent those of their affiliated organizations, or those of the publisher, the editors and the reviewers. Any product that may be evaluated in this article or claim that may be made by its manufacturer is not guaranteed or endorsed by the publisher.

Authors

  • P. Piemontese Neonatal Intensive Care Unit (NICU), Department of Clinical Science and Comunity Health, Fondazione IRCCS ‘‘Ca’ Granda’’ Ospedale Maggiore Policlinico, University of Milan, Milano, Italy.
  • N. Liotto Neonatal Intensive Care Unit (NICU), Department of Clinical Science and Comunity Health, Fondazione IRCCS ‘‘Ca’ Granda’’ Ospedale Maggiore Policlinico, University of Milan, Milano, Italy.
  • F. Garbarino Neonatal Intensive Care Unit (NICU), Department of Clinical Science and Comunity Health, Fondazione IRCCS ‘‘Ca’ Granda’’ Ospedale Maggiore Policlinico, University of Milan, Milano, Italy.
  • D. Morniroli Neonatal Intensive Care Unit (NICU), Department of Clinical Science and Comunity Health, Fondazione IRCCS ‘‘Ca’ Granda’’ Ospedale Maggiore Policlinico, University of Milan, Milano, Italy.
  • F. Taroni Neonatal Intensive Care Unit (NICU), Department of Clinical Science and Comunity Health, Fondazione IRCCS ‘‘Ca’ Granda’’ Ospedale Maggiore Policlinico, University of Milan, Milano, Italy.
  • B. Bracco Neonatal Intensive Care Unit (NICU), Department of Clinical Science and Comunity Health, Fondazione IRCCS ‘‘Ca’ Granda’’ Ospedale Maggiore Policlinico, University of Milan, Milano, Italy.
  • E. Garavaglia Neonatal Intensive Care Unit (NICU), Department of Clinical Science and Comunity Health, Fondazione IRCCS ‘‘Ca’ Granda’’ Ospedale Maggiore Policlinico, University of Milan, Milano, Italy.
  • F. Mosca Neonatal Intensive Care Unit (NICU), Department of Clinical Science and Comunity Health, Fondazione IRCCS ‘‘Ca’ Granda’’ Ospedale Maggiore Policlinico, University of Milan, Milano, Italy.
Objectives: Preterm infants may develop altered adiposity, a risk factor for metabolic syndrome. The aim was to evaluate if body composition and blood pressure were altered in a cohort of children born preterm followed up to prepubertal age. Methods: Observational, longitudinal, explorative study. Forty children born preterm underwent growth and body composition assessment by an air displacement plethysmography system at term c.a. and at 5 years. BMI, skinfold thicknesses and blood pressure were further measured at 5 years. Inclusion criteria were birth weight <1500 g and gestational age <32 weeks. Exclusion criteria were congenital/chromosomal or surgical diseases. Forty-three healthy children born at term were the reference group. Results: At term c.a. preterm children were lighter (2455±484 g vs 3247±345 g; p<0.001) and shorter (45.6±3.4 cm vs 49.1±2.3 cm; p<0.001) than children born at term and their fat mass was higher (14.8% vs 8.6%; p=0.02). At 5 years of life, weight and height of children born preterm were lower than those of their counterpart (18.328±3.01 vs 20.302±3.01 g; p=0.008 and 109.7±6.5 vs 112.7±4.3 cm; p=0.02, respectively). No difference in percentage of fat mass was detected. Abdominal, subscapular and suprailiac skinfolds (mm) were larger in the preterm group (6.9±3.6 vs 5.3±2.8, p=0.002; 6.5±2.8 vs 5.0±1.6, p=0,01 and 11.8±4.3 vs 9.3±3.8, p=0,01, respectively). Diastolic pressure (mmHg) was higher in the preterm group (62.2 vs 57.5, p=0.01). Conclusions: At prepubertal age children born preterm tend towards a greater truncal adiposity and increased values of diastolic pressure which might have adverse consequences for later health.

Piemontese, P., Liotto, N., Garbarino, F., Morniroli, D., Taroni, F., Bracco, B., Garavaglia, E., & Mosca, F. (2013). Effect of prematurity on fat mass distribution and blood pressure at prepubertal age: a follow-up study. La Pediatria Medica E Chirurgica, 35(4). https://doi.org/10.4081/pmc.2013.36

Downloads

Download data is not yet available.

Citations